环境生物技术研究
发布时间:2014-12-01 作者: 访问量:研究方向
有机污染物的生物降解(闫海)
利用微藻固定二氧化碳并转化生物柴油研究(闫海)
采用环境有益微生物治理修复富营养化天然水体(闫海)
环境污染物的生物检测技术(时国庆)
环境污染的生物标记物(时国庆)
环境化合物的毒理学作用机制(时国庆)
重金属的植物修复(王海鸥)
采用植物治理修复富营养化天然水体(王海鸥)
重金属解毒相关基因、高效磷转运子基因及藻类脂类合成相关基因的研究(王海鸥)
细菌渗透感应与渗透调节机制研究(魏巍)
利用氧化硫硫杆菌等菌种对污泥、硫铁矿、铜矿等脱硫(邱丽娜)
主要研究课题
1.国家自然科学基金“石酸戴尔福特菌降解微囊藻毒素的分子机理研究”(编号:20777008),经费:28万元。(闫海)
2.北京市教委专利转化项目“超高细胞浓度光合细菌的培养与应用研究”,经费:15万元。(闫海)
3.北京市教委共建项目“官厅水库上游妫水湖防止富营养化和蓝藻水华发展的复合生态工程治理研究”,经费:150万元。(闫海)
4.教育部重点项目“食酸戴尔福特菌降解微囊藻毒素的途径与分子机理”,经费:10万元。(闫海)
5.科技部中小企业创新基金“异养发酵培养小球藻生产叶黄素研究”,经费:45万元。(闫海)
6.北京市自然科学基金“北京饮用水源地蓝藻和微囊藻毒素的变化及去除方法研究”,经费:3.5万元。(闫海)
7.北京市教委产业孵化器项目“超高细胞浓度小球藻的培养和人类健康食品的生产”,经费:50万元。(闫海)
8.国家自然科学基金“有机锡对动物蛋白酶体的干扰及下游毒理效应”,经费:33万元。(时国庆)
9.国家自然科学基金“组成毒理学分析仪的研制及其应用”,经费:6万元。(时国庆)
10.国家自然科学基金“环境样品中雌激素活性 化合物的受体亲和色谱分离机毒性鉴定预评估”,经费:10万元。(时国庆)
11.中国石油科技创新基金“利用小球藻固定二氧化碳和生产生物柴油的研究”,经费:20万元。(王海鸥)
代表性研究论文
1.YAN Hai, SUN Xudong, MA Zhao, XIAO Chengbin, Ning Jun. Increase in biodesulfurization activity of dibenzothiophene by Rhodococcus erythropolis USTB-03 using nicotinamide and riboflavin. J. of Environ. Sci.2008, 20: 613-618.
2.Liu Fangyao, Hong Mingzhang, Liu Danmei, Li Yawen, Shou Peishun, Yan Hai and Shi Guoqing. Biodegradation of Methyl Parathion by Acinetobacter radioresistens USTB-04. J. of Environ. Sci. 2007, 19:1257-1260.
3.Hai Yan, Aijun Gong, Hongsheng He, Jie Zhou, Yuxia Wei and Le LV. Adsorption of microcystins by carbon nanotubes. Chemosphere, 2006, 62(1):142-148. *
4.*Yan, H., Pan, G., Hua, Z., Li, X., Chen, H., 2004. Effective removal of microcystins using carbon nanotubes embedded with bacteria. Chinese Science Bulletin 49(16), 1694-1698.
5.Guoqing Shi, Di Chen, Guangshu Zhai, Marina S. Chen, Qiuzhi Cindy Cui, Qunfang Zhou, Bin He, Q. Ping Dou and Guibin Jiang. (2009). The Proteasome Is a Molecular Target of Environmental Toxic Organotins. Environmental Health Perspectives 117:379-386 (IF=6.123)
6.陈曦,时国庆﹡,钟广蓉,陈娟,林森,孙清.三苯基锡对神经细胞蛋白酶体活性与相关蛋白水平的影响.科学通报,2009,54,2962-2966
7.Congde Hou, Guoqing Shi, Wai Har Lam, Di Chen, Quizhi Cindy Cui, Q. Ping Dou and Tak Hang Chan. Semi-synthesis and proteasome inhibition of D-ring deoxy analogs of (-)-epigallocatechin gallate (EGCG), the active ingredient of green tea extract. Can. J. Chem. 2008, 86:495-502
8.时国庆,郭彦峰,魏巍,宋青,张怀,钟广蓉,雌激素ERβ配体结合区的异源表达与纯化,北京科技大学学报,2007,29(S2),208-211
9.Yang Huanjie, Shi Guoqing,Dou Qingping, The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from “Indian winter cherry”.Mol Pharmacol. 2007,71(2):426-437
10.Haiou W, Xiaoquan S, Bei W, Shuzhen Z. Preliminary characterization of light rare earth element-binding peptide of a natural perennial fern Dicranopteris dichotoma. Analytical and Bioanalytical chemistry, 2003, 376: 49-52.
11.Xiaoquan S,Haiou W , Shuzhen Z, Bei W. Accumulation and uptake of light rare earth elements in a hyperaccumulator Dicropteris dichotoma. Plant Science, 2003, 165: 1477-1483.
12.Haiou W , Xiaoquan Sh, Bei W, Shu-zhen Z. Responses of Antioxidative Enzymes to Accumulation of Copper in a Copper Hyperaccumulator of Commoelina communis. Arch. Environ. Contam. Toxicol. 2004, 47:185–192.
13. Wei Wei, Zhi Jing Gu, Bo Zhang, Lei Wang and Su Sheng Yang, Cloning and complementation analysis of greA gene involved in salt tolerance of Sinorhizobium meliloti. Annals of Microbiology, 57(2),289-291(2007).
14. 周鈺鋼,魏巍*,Isolation and identification of a strain of salt-tolerant Bacillus sp. 北京科技大学学报, 2007(29)S2:221-222.
15.Wei Wei, Juquan Jiang, Xiaohong Li, Lei Wang and Su Sheng Yang, Isolation of salt-sensitive mutants from Sinorhizobium meliloti and characterization of genes involved in salt tolerance. Letters in Applied Microbiology, 39 (3), 278-283 (2004).